Keratoconus: Symptoms, Causes and Treatment — Brisbane

Side-by-side close-ups of two eyes: the left shows a normal round cornea, while the right depicts keratoconus with a cone-shaped bulge.

Dr Cronin is an internationally recognised keratoconus specialist in Brisbane. He treats patients from Queensland, across Australia and internationally, and teaches keratoconus surgery to ophthalmologists around the world.

  • He is regularly invited to speak on keratoconus at international conferences
  • He offers all of the latest evidence-based treatments
  • He is an international expert in CAIRS keratoplasty (Corneal Allogenic Intrastromal Ring Segments)
  • He provided Glaukos Epioxa advanced cross-linking years before it was available in other centres
  • He is involved in numerous international research studies on keratoconus treatment
  • He offers “Athens protocol” topography-guided laser treatment for keratoconus
  • He performs femtosecond laser assisted corneal transplantation techniques such as Deep Anterior Lamellar Keratoplasty

Traditionally 1 in 4 people with keratoconus needed a full thickness corneal transplant. Whilst this is an effective treatment, corneal transplants can reject and fail. Thankfully, with modern treatment, newly diagnosed patients will only very rarely need a corneal transplant: we can now halt the progression of keratoconus and even remove the corneal irregularities with routine surgery.

What Is Keratoconus?

Keratoconus is a progressive inflammatory eye disorder that affects the shape of the cornea, the clear front surface of the eye. A healthy cornea is round like a soccer ball; in keratoconus it gradually thins and bulges outward into a cone-like shape. That irregular shape distorts vision in a way standard glasses often cannot fully correct, making everyday tasks such as reading or driving harder. Symptoms usually begin in the late teens or early twenties, and the condition can worsen over time if left untreated. Keratoconus was once considered rare, quoted at about 1 in 2,000 people, but modern corneal imaging suggests it is far more common, with some studies estimating closer to 1 in 375. It is not the only condition that changes the cornea's shape: see how it differs from keratoglobus and pellucid marginal degeneration.

Keratoconus Symptoms

Symptoms vary from person to person, and in the earliest stages there may be none at all, which is why corneal mapping matters. The common signs are:

  • Blurred or distorted vision that glasses never quite seem to fix
  • Glasses or contact lens prescriptions that keep changing, with steadily increasing astigmatism
  • Ghosting, shadowing or doubled letters, often in one eye
  • Flaring, halos and glare around lights at night, especially oncoming headlights
  • Increased sensitivity to light
  • Itchy eyes and a strong urge to rub them

In established keratoconus the distortion becomes harder to correct with glasses, and rigid or scleral contact lenses are often needed to see well. If any of this sounds familiar, a corneal map will give you a definitive answer.

What Causes Keratoconus?

Keratoconus is driven by inflammation that weakens the collagen framework of the cornea. Eye rubbing is the single biggest modifiable risk factor: the mechanical trauma of vigorous, repeated rubbing both triggers and accelerates the disease, and it is usually driven by the itch of allergy. Genetics load the dice, with about 1 in 10 patients having an affected family member, which is why we recommend screening children of keratoconus patients from around age 10. Allergic conditions such as hay fever, eczema and asthma travel with keratoconus, and it is also more common in people with Down syndrome, sleep apnoea and some connective tissue disorders. For the full picture, read what causes keratoconus, and if you are planning a family, see keratoconus and pregnancy.

How Keratoconus Is Diagnosed

Early keratoconus cannot be picked up from a reading chart alone. The diagnosis is made by mapping the cornea: corneal topography maps the surface shape, and tomography (Pentacam) maps the full thickness profile, picking up the earliest thinning and steepening long before vision changes. At the Queensland Eye Institute we also measure corneal biomechanics, which can reveal a weak cornea before its shape has visibly changed. Read more about how topography and tomography detect keratoconus.

How Quickly Does Keratoconus Progress?

Keratoconus progresses fastest in teenagers and young adults, which is why a new diagnosis in a young person should be acted on quickly; our guide for parents of teenagers with keratoconus covers this in detail. Progression typically slows through the thirties and forties, but no individual's course can be assumed, so stability is tracked with corneal scans every three to twelve months. In advanced disease, a sudden painful swelling of the cornea called hydrops can occur, which is one more reason to stop progression early. The goal of modern care is simple: catch it early, stabilise it, and keep the vision you have.

Stages of keratoconus

Keratoconus is commonly described as mild (vision still corrects well with glasses), moderate (distortion needs rigid or scleral contact lenses) and advanced (significant thinning, steepening or scarring, where surgery is usually discussed). The stage guides which treatments make sense, but the more important question at any stage is whether the cornea is still changing.

Preparing for Your Assessment

Keratoconus Assessment Preparation

This video will help you to prepare for your keratoconus assessment appointment with Dr Cronin.

Keratoconus Treatment Options

Treatment has two jobs: stopping the disease and restoring vision. Which combination is right for you depends on how advanced the keratoconus is and whether it is still progressing. At a glance:

Each option is covered in more detail below.

Non-Surgical Management
01Stop Rubbing Your Eyes
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Many patients with keratoconus have a long history of rubbing their eyes due to chronic allergy. This rubbing, can severely worsen keratoconus and should be strictly avoided.

It is imperative that you stop rubbing your eyes if you have keratoconus.

Topical anti-histamine drops such as Olopatidine, Ketotifen or sodium cromoglycate may be helpful in relieving the chronic irritation and itch.

02Contact Lenses
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Most patients with keratoconus require specially fitted contact lenses to have good vision. However, some patients may not tolerate contact lenses and may require alternative treatment options. These contact lenses should provide excellent vision but do not treat the actual disease.

Generally, specially trained contact lens optometrists are required to fit these lenses. These optometrists have the specialised equipment and expertise to fit complex contact lenses for keratoconus.

Surgical Interventions
03Collagen Cross-Linking
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Patients with worsening keratoconus can have their progression halted with corneal collagen cross-linking (CXL). Corneal cross-linking works by applying riboflavin drops (vitamin B2) to the cornea, which are then activated by ultraviolet light. This reaction increases the number of cross links between collagen fibres, creating strong, permanent bonds that substantially strengthen the cornea and stop the progression of the disease.

Corneal cross-linking is an advanced procedure for strengthening the cornea and is effective in halting keratoconus progression. The procedure can be performed as an outpatient procedure if you do not have private health insurance. This means you can maximise your medicare rebates with the medicare safety net. If you have health insurance then Dr Cronin performs the procedure in a hospital to minimise the cost of corneal collagen cross linking.

Dr Cronin uses the best collagen cross linking machine available. The revolutionary eye tracking technology in the Glaukos KXL2 topography guided collagen cross linking machine means that more energy is delivered to the steeper parts of your cornea. This personalised and customised treatment is individual for each person. It delivers better vision and better outcomes to more patients. Dr Cronin and his colleagues at QEI are the only surgeons in Australia with this amazing cross linking technology called Glaukos Epioxa.

Sometime people are told that their cornea is “too thin” for corneal collagen cross-linking. This is a very outdated approach. Advanced evidence based cross-linking can be safely performed on thin corneas.

Glaukos KXL2 Machine
04Laser Corneal Resurfacing & CXL ("Athens Protocol")
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This involves using an excimer laser to “resurface” the affected cornea and remove the irregular astigmatism that causes the reduced vision in keratoconus. This is called a phototherapeutic keratectomy (PTK) and it leaves the cornea with a nice regular shape.

Immediately after the laser resurfacing has occurred, the cornea may undergo collagen cross-linking, which increases the number of cross links within the corneal structure, enhancing its strength and stability. So, can you have laser eye surgery if you have keratoconus? Yes! But not in all cases and you will need an individual assessment with Dr Cronin to assess your suitability.

See a video of the procedure here.

05CAIRS (Corneal Allogenic Intrastromal Ring Segment)
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In this type of corneal transplant procedure, a femtosecond laser is used to create a ring-shaped tunnel in your cornea. A small, similar shaped ring of donor corneal tissue is threaded into the tunnel in your cornea. This ring of corneal tissue improves the strength, rigidity and overall shape of your cornea. CAIRS keratoplasty can be combined with collagen cross linking to enhance the strengthening effect.

CAIRS has many of the advantages of both Kerarings and other types of corneal transplants without many of the downsides. CAIRS offers tailored solutions for patients with keratoconus, providing personalized treatment options based on individual needs. QEI was the first clinic in Australia to offer CAIRS as a treatment and Dr Cronin regularly hosts surgeons from around the world to teach this technique.

He even runs a website that is used by surgeons globally to plan their CAIRS keratoplasty procedures - www.cairsplan.com.

Watch a video of the CAIRS procedure here.

06Bowman’s Membrane Transplantation
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Bowman's layer is a tough but clear layer in the cornea. In a normal cornea it is approximately 10 microns thick but it is often weakened and degraded in keratoconus. Bowman's membrane transplantation is considered for patients with progressive keratoconus who require additional corneal strengthening - especially if there eye is too thin for cross-linking.

In a Bowman's layer transplant this 10 micron layer is delicately peeled from a donor cornea. A femtosecond laser is used to create a pocket in your cornea. The donor Bowman's layer is then inserted into this pocket. This strengthens and stiffens your cornea. Bowman's layer transplantation is a very niche and rarely used treatment.

Bowman's Membrane Transplant
07Plastic Corneal Segments (Kerarings)
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Plastic corneal segments, such as Kerarings or intact, are one method for treating keratoconus by reshaping the cornea. These small implants are inserted into your cornea to pull the keratoconic cornea back into a better shape, much like “CAIRS” as discussed above.

CAIRS has completely replaced Kerarings as a procedure for keratoconus as it is safer and more reliable.

08Corneal Transplantation
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Corneal transplantation is typically considered when glasses or contact lenses and other treatments are no longer effective in managing keratoconus. With all of the other treatments available this is a last resort treatment for NEWLY diagnosed patients but is still a very common procedure for patients who already have severe keratoconus.

New partial thickness corneal grafting techniques such as Deep Anterior Lamellar Keratoplasty (“DALK”) have much lower rejection rates than traditional full thickness or Penetrating Keratoplasty procedures.

Why Patients Choose Dr Cronin for Keratoconus

If you are looking for a keratoconus specialist in Brisbane, it is worth knowing what sits behind the title. Dr Cronin:

  • Is a Fellow of the Royal Australian and New Zealand College of Ophthalmologists and a Founding Fellow of the World College of Refractive Surgery and Visual Sciences
  • Teaches CAIRS keratoplasty to surgeons internationally, co-authored the Brisbane Nomogram for CAIRS surgical planning, and co-developed cairsplan.com, the planning platform used by CAIRS surgeons worldwide
  • Was Australia's first surgeon to offer Glaukos Epioxa epi-on cross-linking, and one of only 14 surgeons worldwide given early access to the Mosaic topography-guided cross-linking system
  • Co-authored the 2024 Journal of Cataract and Refractive Surgery study of topography-guided cross-linking in which 60% of patients improved their best corrected vision
  • Is the Director of Education at the Queensland Eye Institute and leads international research studies on keratoconus treatment

You can read more about Dr Cronin, or about the procedures themselves on the cross-linking and CAIRS pages.

Keratoconus Treatment Costs

If your health fund covers cross-linking (Medicare item number 42652), you can have your procedure performed while lightly sedated or asleep at the South Brisbane Day Hospital with NO GAP for the anaesthetist.

Cross-linking for progressive keratoconus attracts a Medicare rebate, and CAIRS is recognised by Medicare as a keratoplasty under item 42653, following a campaign Dr Cronin led. For patients without private health insurance, cross-linking can be performed in the outpatient procedure room at the Queensland Eye Institute, which makes the most of the Medicare Safety Net. The cross-linking cost guide explains the fees, rebates and what is included.

Choosing the Right Treatment

Not every treatment is appropriate for every eye. The right plan depends on how advanced the keratoconus is, whether it is still progressing, your vision in each eye and what you need your eyes to do. Dr Cronin will map your corneas, explain exactly where you stand, and set out which treatments will genuinely help, and in what order, at your consultation.

Book a Keratoconus Assessment

Frequently Asked Questions

What is keratoconus?

Keratoconus is a progressive inflammatory eye condition in which the cornea, the clear front window of the eye, thins and bulges into a cone shape. The irregular shape distorts vision in a way glasses often cannot fully correct. It usually appears in the teens or twenties, and modern treatment can stop it progressing.

What are the first signs of keratoconus?

Typically blurred or distorted vision that keeps changing, glasses prescriptions that never seem to stay right, rising astigmatism, ghosting or shadowing of letters in one eye, and flaring or halos around lights at night. Itchy eyes and frequent eye rubbing often go with it. Anyone with these symptoms, especially with a family history, should have corneal mapping.

How quickly does keratoconus progress?

It progresses fastest in teenagers and young adults, which is why early diagnosis matters most at that age. Progression usually slows through the thirties and forties, but it cannot be predicted in any individual, so regular corneal scans every three to twelve months are used to track stability. If scans show progression, cross-linking can stop it.

Can keratoconus make you blind?

Keratoconus very rarely causes total blindness. Untreated, however, it can cause severe vision impairment through corneal distortion and scarring, to the point where a corneal transplant is needed. Caught early and stabilised with cross-linking, the vast majority of patients keep good, functional vision for life.

Can I drive with keratoconus?

Most people with keratoconus can drive, provided their corrected vision meets the driving standard, with glasses or contact lenses if needed. Advanced keratoconus can make night driving difficult because of glare and halos around headlights. Your vision is checked against the driving standard at assessment, so you will know exactly where you stand.

When should I see a keratoconus specialist?

As soon as keratoconus is suspected, and promptly after diagnosis, because the treatment that stops progression works best before vision is lost. See a specialist if your prescription keeps changing, your astigmatism keeps rising, an optometrist has flagged an unusual corneal map, or you have a family history and rub your eyes. Teenagers with these signs should be seen quickly.

Can keratoconus be cured?

There is no "cure," but progression can be completely stopped. Corneal Collagen Cross-Linking (CXL) is the gold standard treatment to harden the cornea and halt the disease. If caught early, you will likely never need a transplant. Dr Cronin’s topography guided epithelium-on, oxygen enhanced cross-linking provides a faster recovery and better visual outcomes than standard corneal collagen cross-linking.

What is the "Athens Protocol" for keratoconus that Dr. Cronin uses?

The Athens Protocol is a combination treatment performed in a single session: 1) Topography-Guided Laser (to smooth the irregular corneal shape) followed by 2) Cross-Linking (to lock that new shape in). This offers better visual rehabilitation than cross-linking alone.

What is CAIRS for keratoconus in Brisbane Australia?

CAIRS (Corneal Allogenic Intrastromal Ring Segments) is a revolutionary technique where donor corneal tissue is implanted into the cornea to flatten the cone and improve vision. Unlike synthetic plastic rings (Intacs), CAIRS rings are natural tissue, reducing the risk of extrusion or rejection.

Is keratoconus genetic? Will my children get it?

There is a genetic link. About 1 in 10 patients has a family member with the condition. We recommend screening children of keratoconus patients starting at age 10, or sooner if they show signs of frequent eye rubbing or changing vision.

Can I rub my eyes if I have keratoconus?

Absolutely not. Eye rubbing is the single biggest risk factor for worsening keratoconus. Dr. Cronin can prescribe anti-allergy drops to stop the itch, but you MUST break the rubbing habit to save your vision.

Further reading

Written and reviewed by Dr Brendan Cronin FRANZCO, FWCRS — Corneal, Cataract and Refractive Surgeon.

Last reviewed: 25 October 2026